Maternal BMI and Glycemia Impact the Fetal Metabolome
نویسندگان
چکیده
منابع مشابه
Maternal BMI and Glycemia Impact the Fetal Metabolome.
OBJECTIVE We used targeted metabolomics to determine associations of maternal BMI and glucose levels with cord blood metabolites and associations of cord blood metabolites with newborn birth weight and adiposity in mother-offspring dyads. RESEARCH DESIGN AND METHODS Targeted metabolomic assays were performed on cord blood serum samples from European ancestry, Afro-Caribbean, Thai, and Mexican...
متن کاملErratum. Maternal BMI and Glycemia Impact the Fetal Metabolome. Diabetes Care 2017;40:902–910
1. In the RESEARCH DESIGN AND METHODS section of the abstract, the sentence was corrected to read: “Targeted metabolic assays were performed on cord blood plasma samples from European ancestry, Afro-Caribbean, Thai, and Mexican American newborns (400 from each ancestry group) whose mothers participated in the Hyperglycemia and Adverse PregnancyOutcome (HAPO) Study andwho had anthropometric meas...
متن کاملThe impact of maternal obesity on maternal and fetal health.
The increasing rate of maternal obesity provides a major challenge to obstetric practice. Maternal obesity can result in negative outcomes for both women and fetuses. The maternal risks during pregnancy include gestational diabetes and preeclampsia. The fetus is at risk for stillbirth and congenital anomalies. Obesity in pregnancy can also affect health later in life for both mother and child. ...
متن کاملInfluence of moderate maternal nutrition restriction on the fetal baboon metabolome at 0.5 and 0.9 gestation.
BACKGROUND AND AIMS Moderately reduced maternal nutrient availability during pregnancy has adverse effects on the fetuses' growth and metabolism during and after pregnancy. The aim of this study was to explore effects of maternal nutrition restriction (MNR) on key metabolites of the fetal energy metabolism, particularly amino acids (AA), nonesterified fatty acids (NEFA), acylcarnitines and phos...
متن کاملImpact of maternal obesity on fetal health.
The obesity epidemic is a problem of global importance with a profound impact on maternal-fetal health. Maternal overweight and obesity causes pregnancy complications such as gestational diabetes, hypertension and preeclampsia and affects fetal growth. Maternal obesity offers an altered genetic, hormonal and biochemical environment for the developing fetus/embryo and influences fetal growth and...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Diabetes Care
سال: 2017
ISSN: 0149-5992,1935-5548
DOI: 10.2337/dc16-2452